Niacinamide
Vitamin B3, Nicotinamide
AStrong clinical evidence (multiple RCTs)Safety: Safe
Chemical Function
Multifunctional B vitamin that improves barrier function, reduces transepidermal water loss, and brightens.
Scientific Evidence
Multiple RCTs show 2-5% niacinamide reduces fine lines, hyperpigmentation, and redness.
Quality of EvidenceStrong
Interactions
Generally well-tolerated; pairs well with retinol, hyaluronic acid, and peptides. May reduce irritation from stronger actives.
Pro-Aging Relevance
Strengthens the barrier and fades age spots — central concerns for women 40+.
The Science Behind Niacinamide
Niacinamide is vitamin B3 in a stable, water-soluble form. It helps skin make more ceramides, calms redness, and fades uneven tone. It is one of the most compatible actives — it rarely conflicts and often soothes the effects of stronger ingredients.
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