Ceramides
Sphingolipids
AStrong clinical evidence (multiple RCTs)Safety: Safe
Chemical Function
Lipids that form the skin barrier.
Scientific Evidence
Extensive evidence that ceramides restore barrier and reduce water loss, especially in a 3:1:1 ratio with cholesterol and fatty acids.
Quality of EvidenceStrong
Interactions
Universal; the foundation of any routine.
Pro-Aging Relevance
Replaces the ceramides lost with age and hormonal change.
The Science Behind Ceramides
Ceramides are the mortar between your skin cells. Aging and menopause reduce them, weakening the barrier. A 3:1:1 ratio of ceramides, cholesterol, and fatty acids restores it so other actives can work.
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